Can you take Lexapro® with Xanax®?

Evidence-based interaction check between Lexapro® and Xanax®

1 known interaction

The most significant is rated moderate. Always discuss with your healthcare provider.

CYP3A4 inhibition increases alprazolam levels by 50–100%, worsening sedation and dependence risk.

Check another pair

1 interaction found

Moderate

CYP3A4 inhibition increases alprazolam levels by 50–100%, worsening sedation and dependence risk.

What this means

This summary is based on published interaction data from FDA prescribing information and clinical literature. It does not account for individual health factors, dosages, or other medications you may be taking. Always consult a qualified healthcare provider before making changes to your medication regimen.

Frequently Asked Questions

Is it safe to take Lexapro® with Xanax®?

Our database shows 1 documented interaction between Lexapro® and Xanax®. The most significant is rated as "moderate." Always discuss your specific medications with your healthcare provider.

What happens if you take Lexapro® and Xanax® together?

Taking Lexapro® and Xanax® together may cause the following: CYP3A4 inhibition increases alprazolam levels by 50–100%, worsening sedation and dependence risk.. Your doctor can advise on dosage adjustments or alternatives.