Evidence-Based Lifestyle Medicine
Meets Transparent Medication Data.
EvidentMeds gives MAHA ELEVATE clinics the evidence layer they need: transparent medication profiles with clinical trial funding disclosed, lifestyle intervention evidence ratings, and pharmacogenomics context — so deprescribing decisions are evidence-driven, not guesswork.
What Is CMS MAHA ELEVATE?
Make America Healthy Again — Evaluating Lifestyle, Education, and Verified Alternative Treatment Efficacy is a CMS initiative funding 30 community health organizations to rigorously test whether structured lifestyle interventions can reduce chronic disease burden. The program launches September 2026.
30 CMS Awardees
Community health organizations selected to implement structured lifestyle + medication optimization programs
Evidence-Driven
Each program must demonstrate measurable outcomes — reduced HbA1c, weight loss, medication reduction, improved biomarkers
Not Anti-Medication
MAHA ELEVATE is not about removing medications. It's about ensuring every prescription is justified by evidence, not habit
Evidence Brief Generator
Search for a specific medication or select a condition to generate a data-driven evidence brief. Each brief pulls real cost, efficacy, side effect, and lifestyle alternative data from our directory.
Pre-diabetes / Metabolic Syndrome
Evidence Brief for MAHA ELEVATE Program Design — 3 medications analyzed
Medications — Cost, Efficacy & Lifestyle Alternatives
Low-carb diet: Comparable A1C reduction to metformin
Weight loss (5-10%): -0
Exercise: Improves insulin sensitivity 48-72h per session
Very low-carbohydrate diet (<50g/day) — Strong
Mediterranean diet — Strong
Resistance training (3×/week) — Strong
Ketogenic Diet (<20g net carbs/day): HbA1c -1
Time-Restricted Eating (16:8 or OMAD): Improves fasting insulin, HbA1c, and visceral fat independently of caloric restriction
Resistance Training (3×/week): Increases GLUT4 transporter density in muscle; glucose disposal increases 48%; HbA1c improves independently of weight loss; reduces visceral adipose tissue
Low-carbohydrate diet — Strong
Intermittent fasting (16:8 or 5:2) — Strong
Mediterranean diet — Strong
Ketogenic Diet (<20g net carbs/day): HbA1c reduction 1
Resistance Training (3×/week): Increases GLUT4 transporter density; glucose disposal increased 48%; improvements persist 48–72 hours per session
Time-Restricted Eating (16:8): Improves fasting insulin, HbA1c, and visceral fat independently of caloric restriction
Phase 2: Outcomes Tracking Insight
Real-time biometric data can show patients their actual physiological response to interventions — a powerful motivational tool that increases adherence compared to standard counseling alone.
Key Studies Referenced
UKPDS (gold standard), DPP, Cochrane meta-analysis · SUSTAIN-1 through SUSTAIN-10, PIONEER, SELECT, STEP program · EMPA-REG OUTCOME (2015), EMPEROR-Reduced (2020), EMPEROR-Preserved (2021)
Full medication profiles include clinical trial funding sources, side effect rates, tapering protocols, pharmacogenomics data, and comprehensive alternative evidence ratings.
Phase 2: Outcomes Tracking Platform
Phase 1 gives clinicians transparent evidence. Phase 2 will prove that evidence-based interventions are actually working — with objective, real-time patient data and CMS-ready reporting.
Real-Time Patient Data
Objective, continuous health metrics — not self-reported logs
Measurable Outcomes
Prove lifestyle interventions are working with hard data
CMS-Ready Reporting
Aggregate outcomes formatted for program compliance
Early Access for MAHA ELEVATE Partners
Clinics partnering early receive priority access to our outcomes tracking platform and a full walkthrough of the technology stack. Reach out to learn more.
Request a WalkthroughFrequently Asked Questions
What is CMS MAHA ELEVATE?
MAHA ELEVATE (Make America Healthy Again — Evaluating Lifestyle, Education, and Verified Alternative Treatment Efficacy) is a CMS initiative funding 30 community health organizations to test whether structured lifestyle interventions can reduce chronic disease burden alongside — or in some cases instead of — long-term medication use. The program begins September 2026.
How does EvidentMeds support MAHA ELEVATE clinics?
EvidentMeds provides the evidence layer: transparent, citation-backed medication profiles with clinical trial funding disclosure, lifestyle alternative evidence ratings, and pharmacogenomics context. Clinicians use this to make evidence-based deprescribing and lifestyle intervention decisions. Our Phase 2 platform (launching 2026) will add real-time outcomes tracking so clinics can prove their interventions are working.
Is EvidentMeds anti-medication?
No. EvidentMeds is pro-evidence. Many medications are life-saving and irreplaceable. Our role is to ensure clinicians and patients have transparent access to clinical trial data, funding sources, and lifestyle alternatives — so treatment decisions are informed, not influenced by marketing. We follow the evidence wherever it leads.
Does EvidentMeds store patient health information (PHI)?
Phase 1 (current) stores no patient data whatsoever. It is a public evidence library. Phase 2 (outcomes tracking) will be built on HIPAA-compliant infrastructure with BAA agreements, and will be a separate authenticated platform. Contact us for a full walkthrough of the Phase 2 architecture.
What does EvidentMeds cost?
Phase 1 — the public medication evidence directory — is completely free. There is no cost to access medication profiles, clinical trial funding data, lifestyle alternative evidence, or the evidence brief generator. Phase 2 (outcomes tracking with device integration) pricing will be announced closer to launch; early MAHA ELEVATE partners will receive preferential pricing.
How can our clinic become a MAHA ELEVATE partner?
Contact Solutions 2 Wellness, LLC at info@solutions2wellness.org. We are actively onboarding clinics preparing for the CMS MAHA ELEVATE program. Early partners receive priority access to the Phase 2 outcomes tracking platform and dedicated integration support.
Partner With Us
Whether you're applying for CMS MAHA ELEVATE funding, building a lifestyle medicine program, or integrating deprescribing into your practice — we'd love to hear from you.
Ready to Build an Evidence-Driven Program?
Explore our medication directory, then reach out when you're ready to partner.