Can you take Eliquis® with Advil® / Motrin®?

Evidence-based interaction check between Eliquis® and Advil® / Motrin®

2 known interactions

The most significant is rated major. Always discuss with your healthcare provider.

Dramatically increases bleeding risk through additive anticoagulation and GI mucosal damage. Avoid combination; acetaminophen is safer for pain.
Increased bleeding risk, use sparingly

Check another pair

2 interactions found

Major

Dramatically increases bleeding risk through additive anticoagulation and GI mucosal damage. Avoid combination; acetaminophen is safer for pain.

Moderate

Increased bleeding risk, use sparingly

What this means

This summary is based on published interaction data from FDA prescribing information and clinical literature. It does not account for individual health factors, dosages, or other medications you may be taking. Always consult a qualified healthcare provider before making changes to your medication regimen.

Frequently Asked Questions

Is it safe to take Eliquis® with Advil® / Motrin®?

Our database shows 2 documented interactions between Eliquis® and Advil® / Motrin®. The most significant is rated as "major." Always discuss your specific medications with your healthcare provider.

What happens if you take Eliquis® and Advil® / Motrin® together?

Taking Eliquis® and Advil® / Motrin® together may cause the following: Dramatically increases bleeding risk through additive anticoagulation and GI mucosal damage. Avoid combination; acetaminophen is safer for pain.; Increased bleeding risk, use sparingly. Your doctor can advise on dosage adjustments or alternatives.